Current Research Studies - Pediatrics

For additional information on pediatric clinical research studies, or to inquire about enrollment, contact the OSF HealthCare Children’s Hospital of Illinois  at (309) 655-7171.

For general inquiries about other pediatric clinical research being conducted at OSF HealthCare locations, contact us at  osf.clinicalresearch@osfhealthcare.org.

Sickle Cell Disease

  • Sickle Cell Clinical Research and Intervention Program (SCCRIP)

  • Summary: The purpose of this study is to establish a longitudinal clinical cohort of patients with sickle cell disease (SCD) to serve as a research resource to facilitate evaluation of health outcomes in SCD from pediatric care into adulthood.

    Investigator: Kay Saving, MD

    Location: The Jim & Trudy Maloof St. Jude Affiliate Clinic at OSF Children's Hospital of Illinois, Peoria, Illinois

    ClinicalTrials.gov: 

    Contact: Nicki Bohnker, 309-624-4015, Karen.M.Blatter@osfhealthcare.org

  • Hydroxyurea Optimization through Precision Study (HOPS)

  • Summary: This is a prospective, multi-center, randomized trial that will directly compare a novel, individualized dosing strategy of hydroxyurea to standard weight-based dosing for children with SCA. The primary objective of the study is to evaluate whether a pharmacokinetics-based starting hydroxyurea dose results in superior fetal hemoglobin response vs standard weight-based initial dosing.

    Investigator: Kay Saving, MD

    Location: The Jim & Trudy Maloof St. Jude Affiliate Clinic at OSF Children's Hospital of Illinois, Peoria, Illinois

    ClinicalTrials.gov: 

    Contact: Nicki Bohnker, 309-624-4015, Karen.M.Blatter@osfhealthcare.org