Pulmonary and Critical Care

For any further information on clinical research studies, or to inquire about enrollment, contact us at osf.clinicalresearch@osfhealthcare.org.

COPD/Emphysema

PNEUMRX
CLN0009 PneumRx RePneu Lung Volume Reduction Coil (RePneu LVRC) System. Lung Volume Reduction coil for treatment in patients with Emphysema (RENEW) study.

SPIRATION
IBV Valve System Humanitarian Device for use in the Control of Air Leaks

PNEUMRX Crossover
CLN0016 PneumRx RePneu Lung Volume Reduction Coil (RePneu LVRC) System,   LVRC IDE Crossover Study—(crossover from IDE Trial CLN0009, Lung Volume Reduction Coil Treatment in Patients with Emphysema (RENEW) Study, IDE G110066).

Cystic Fibrosis

Celtaxsys, Inc
Protocol CTX-4430-CF-201:  A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety, and Tolerability of CTX-4430 Administered Orally Once-Daily for 48 Weeks in Adult Patients with Cystic Fibrosis

CFFT Cystic Fibrosis Therapeutics Development Network
STOP2-IP-15:  Standardized Treatment of Pulmonary Exacerbations II (STOP2)

Vertex Pharmaceuticals Incorporated
Protocol VX16-152-102:  A Phase 2, Randomized, Double-blind, Controlled Study to Evaluate the Safety of VX-152 Combination Therapy in Adults With Cystic Fibrosis

Pulmonary Disease/Critical Care Medicine

Influenza Treatment
National Institute of Allergy and Infectious Diseases (NIAID)
Protocol IRC005: A Randomized Double-Blind, Phase 3 Study Comparing the Efficacy and Safety of High-Titer versus Low-Titer Anti-Influenza Immune Plasma for the Treatment of Severe Influenza A

Sepsis Treatment
Bristol Myers Squibb
Protocol: CA209923 Randomized, Double-Blind, Parallel Group Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-936558 (nivolumab) in Participants with Severe Sepsis or Septic Shock

Interventional Pulmonary

Body Vision Medical LTD
Protocol:  Bronchoscopic Lung Biopsy enhancement with LungVision® device

Veracyte, Inc
Protocol:  Prospective Registry To Evaluate Percepta Bronchial Genomic Classifier Patient Data: The PERCEPTA Registry