Pulmonary and Critical Care

Pulmonary and Critical Care

For additional information on the enrolling clinical research studies listed below, or to inquire about enrollment, contact the individual listed for the study.

For general inquiries about other clinical research being conducted at OSF HealthCare locations, contact us at osf.clinicalresearch@osfhealthcare.org.

Cystic Fibrosis

  • TEACH-IP-15: Testing the Effect of Adding Chronic Azithromycin to Inhaled Tobramycin. A randomized, placebo-controlled, double-blinded trial of azithromycin 500mg thrice weekly in combination with inhaled tobramycin

  • Summary: This is a study to examine the effect of combining chronic oral azithromycin with inhaled tobramycin in adolescent and adult subjects with cystic fibrosis who are chronically infected with P. aeruginosa.

    Investigator: Subramanyam Chittivelu

    Location: OSF HealthCare Saint Francis Medical Center, Peoria, Illinois

    ClinicalTrials.gov:  NCT01652157

    Contact: Ashley Scott, (309) 624-2409,  ashley.scott@osfhealthcare.org

  • CFFC-OB-11: A Long-Term Prospective Observational Safety Study of the Incidence of and Risk Factors for Fibrosing Colonopathy in US Patients with Cystic Fibrosis Treated with Pancreatic Enzyme Replacement Therapy: A Harmonized Protocol Across Sponsors

  • Summary: This is a long-term study in cystic fibrosis patients who are participating in the Cystic Fibrosis Patient Registry to assess the occurrence and risk factors for a rare bowel disorder called fibrosing colonopathy (narrowing of the large intestine). Patients will be followed at their regular clinical care visits over a 10-year period and approached if they develop symptoms of fibrosing colonopathy for collection and use of further detailed information.

    Investigator: Heather McLauchlan

    Location: OSF HealthCare Saint Francis Medical Center, Peoria, Illinois

    ClinicalTrials.gov:  NCT01652157

    Contact: Ashley Scott, (309) 624-2409,  ashley.scott@osfhealthcare.org

  • GALAXY-OB-18: Multicenter study of patient-reported gastrointestinal symptoms in people with Cystic Fibrosis

  • Summary: This prospective, multicenter, observational study is designed to assess the feasibility of conducting electronic patient-reported outcomes outside of the clinic on quality of life measures and gastrointestinal symptoms in patients with cystic fibrosis.

    Investigator: Subramanyam Chittivelu

    Location: OSF HealthCare Saint Francis Medical Center, Peoria, Illinois

    Contact: Ashley Scott, (309) 624-2409,  ashley.scott@osfhealthcare.org

  • STOP2: Standardized Treatment of Pulmonary Exacerbations II

  • Summary: This study is to evaluate the effectiveness and safety of differing durations of IV treatment, given in the hospital or at home, for a pulmonary exacerbation in adult patients with cystic fibrosis.

    Investigator: Subramanyam Chittivelu

    Location: OSF HealthCare Saint Francis Medical Center, Peoria, Illinois

    ClinicalTrials.gov:  NCT01652157

    Contact: Ashley Scott, (309) 624-2409,  ashley.scott@osfhealthcare.org

Interventional Pulmonary

  • IBV Valve System (Humanitarian Use Device)

  • Summary: For the control of prolonged air leaks of the lung, or significant air leaks that are likely to become prolonged following lobectomy, segmentectomy, or lung volume reduction surgery

    Investigator: Patrick Whitten

    Location: OSF HealthCare Saint Francis Medical Center, Peoria, Illinois

    Contact: Ashley Scott, (309) 624-2409, ashley.scott@osfhealthcare.org