OSF HealthCare Illinois Neurological Institute

Publications From the INI


Basic Science

Lan YY, Londono D, Bouley R, Rooney MS, Hacohen N: Dnase2a deficiency uncovers Lysosomal clearance of damaged nuclear DNA via autophagy: Cell Reports 9:1-13, 2014

Infectious Disease

Farrell JJ, Tsung AJ, Flier L, Martinez DL, Beam SB, Chen C, Lowery KS, Sampath R, Bonomo RA: PCR and electrospray ionization mass spectrometry for detection of persistent enterococcus faecalis in cerebrospinal fluid following treatment of postoperative ventriculitis.  J Clin Microbiol  51(10):3464-3466, 2013
Vachhani JA, Lee WC, Desanto JR, Tsung AJ: Magnetic resonance spectroscopy imaging characteristics of cerebral Blastomycosis. Surg Neurol Int  5:80, 2014

Memory & Brain Wellness

Salma A, Vasilakis M, Tracy PT: Deep brain stimulation for cognitive disorders: insights into targeting nucleus basalis of meynert in Alzheimer’s disease. World Neurosurg 81(1): e4-5, 2014

Multiple Sclerosis

Valenzuela RM, Pula JH, Garwacki D, Cotter J, Kattah JC: Cryptococcal meningitis in a multiple sclerosis patient taking natalizumab. J Neurol Sci 340(1-2):109-111, 2014

Beh SC, Saber Tehrani AS, Kheradmand A, Zee D. Damping of monocular pendular nystagmus with vibration in a patient with multiple sclerosis. Neurology, 82(15)1380-1381, 2014


Crockett CD, Ruggieri A, Gujrati M, Zallek CM, Ramachandran N, Minassian BA, Moore SA: Late adult-onset of X-linked myopathy with excessive autophagy. Muscle Nerve 50(1): 138-144, 2014


Velpula KK, Dasari VR, Tsung AJ, Dinh DH, Rao J: Transcriptional repression of Mad-Max complex by human umbilical cord blood stem cells downregulates extracellular signal-regulated kinase in glioblastoma. Stem Cells Dev 21(10):1779-1793, 2012
Malla RR, Gopinath S, Gondi CS, Alapati K, Dinh DH, Tsung AJ, Rao: uPAR and cathespin B downregulation induces apoptosis by targeting calcineurin A to BAD via Bci-2 in glioma. J Neurooncol 107(1): 69-80, 2012
Velpula KK, Dasari VR, Tsung AJ, Dinh DH, Rao JS: Cord blood stem cells revert glioma stem cell EMT by downregulating transcriptional activation of Sox2 and Twist1. Oncotarget 2(12):e31844, 2012
Velpula KK, Dasari VR, Asuthkar S, Gorantala B, Tsung AJ: EGFR and c-Met cross talk in glioblastoma and its regulation by human cord blood stem cells. Transl Oncol 5(5):379-392, 2012
Veeravalli KK, Ponnala S, Chetty C, Tsung AJ, Gujrati M, Rao JS: Integrin α9β1-mediated cell migration in glioblastoma via SSAT and Kir4.2 potassium channel pathway. Cell Signal 24:272-281, 2012
Mattei T, Tsung A: A better source of therapeutic stem cells. World Neurosurg 77(1):11-12, 2012
Dasari VR, Velpula KK, Alapati K, Gujrati M, Tsung AJ: Cord blood stem cells inhibit epidermal growth factor receptor translocation to mitochondria in glioblastoma. PLoS One 7(2):e31844, 2012
Velpula KK, Bhasin A, Asuthkar S, Tsung AJ: Combined targeting of PDK 1 and EGFR triggers regression of glioblastoma by reversing the Warburg effect. Cancer Res 73(24): 7277-7289, 2013
Velpula K, Gogineni VR, Nalla AK, Dinh DH, Rao JS: Radiation-induced hypomethylation triggers urokinase plasminogen activator (uPA). Neoplasia. 15(2):192-203, 2013
Martinez DL, Gujrati M, Geoffroy F, Tsung AJ: Isolated CNS Hodgkin's lymphoma: implications for tissue diagnosis. CNS Onc 3(6): 383-387, 2014
Velpula KK, Tsung AJ: PDK1: a new therapeutic target for glioblastoma? CNS Oncol 3(3): 177-179, 2014
Prabhakar S, Asuthkar S, Lee W, Chigurupati S, Zakharian E, Tsung AJ, Velpula KK: Targeting DUSPs in glioblastomas – wielding a double-edged sword? Cell Biol Int 38(2): 145-153, 2014
Dasari VR, Veeravalli KK, Dinh DH: Mesenchymal stem cells in the treatment of spinal cord injuries: A review. World J Stem Cells 6 (2): 120-133, 2014
Chelluboina B, Klopfenstein JD, Pinson DM, Wang DZ, Veeravalli KK: Stem cell treatment after cerebral ischemia regulates the gene expression of apoptotic molecules. Neurochem Res 39(8): 1511-1521, 2014
Hall MD, McGee JL, McGee MC, Hall KA, Neils DM, Klopfenstein JD, Elwood PW: Cost-effectiveness of stereotactic radiosurgery with and without whole-brain radiotherapy for the treatment of newly diagnosed brain metastases. J Neurosurg (Suppl 2). 121:84-90


Keung BM, Shah LM, Eckart DE, Digre KB, Chin SS, Warner JE: A mystery case of proptosis, optic neuropathy, and peripheral neuropathy. J Neuroophthalmol 33(1): 77-82, 2013.
Kattah JC, Pula J. Cavernous Sinus Syndromes.  Medscape Reference. Updated February 14, 2014.  Available at: http://emedicine.medscape.com/article/1161710-overview Pituitary tumors.  eMedicine.com, 2001.Update 2013
Pula JH, Fischer M, Kattah JC: Hemifield slide from traumatic optic chiasmopathy. J Clin Neurosci. 21(8):1446-7, 2014.
Pula JH, Kattah JC, Keung B, Wang H, Daily J: Longitudinally extensive optic neuritis in neuromyelitis optica spectrum. J Neurol Sci. 345(1-2):209-212, 2014
Pula JH, Kattah JC: Ocular pulsations due to posttraumatic compromise of the orbital roof. Neurology 83(8): 771, 2014
Parker S, Gujrati M, Pula J, Zallek SN, Kattah JC. The Heidenhain variant of CJD. A case series. J Neuroophthalmol. Mar; 34(1):4-9, 2014
Mantokoudis G, Saber Tehrani AS, Kattah JC, Eibenberger K, Guede CI, Zee DS, Newman-Toker DE: Quantifying the vestibule-ocular reflex with video-oculography: nature and frequency of artifacts. Audiol Neurotol 20:39-50, 2015


Kattah JC, Nair D, Talkad A, Wang DZ, Fraser K: A case of vestibular and oculomotor pathology from bilateral AICA watershed infarcts treated with basilar artery stenting. Clin Neurol Neurosurg 115: 1098-1101, 2013
Kattah JC, Dhanani SS, Pula JH, Mantokoudis G, Saber Tehrani AS, Newman-Toker DE. Vestibular signs of thiamine deficiency during the early phase of suspected Wernicke encephalopathy. Neurology: Clinical Practice 3 (6): 460-468, 2013
Mantokoudis G, Schubert MC, Saber Tehrani AS, Wong AL, Agrawal Y:Early adaptation and compensation of clinical vestibular responses after unilateral vestibular deafferentation surgery. Otol Neurot 35(1):148-54, 2014
Tehrani AS, Kattah JC, Mantokoudis G, Pula JH, Nair N, Blitz A, Ying S, Newman-Toker DE. Small strokes causing severe vertigo―Frequency of false-negative MRIs and non-lacunar mechanisms. Neurology 83(2):169-73, 2014
Mantokoudis G, Tehrani AS, Wozniak A, Eibenberger K, Kattah JC, Guede CI, Zee DS, Newman-Toker DE: VOR gain by head impulse video-oculography differentiates acute vestibular neuritis from stroke. Otol Neurotol  36(3): 457-465, 2015

Pediatric Neurosciences

Mattei T, Bond B, Sambhara D, Goulart C, Lin J:  Benign extracerebral fluid collection of infancy as a risk factor for development of ‘de novo’ intracranial arachnoid cysts.  J Neurosurg Pediatrics, 12:555-564, 2013
Rammos S, Phillips J, Lin J, Moresco K, Meagher  S. Successful rheolytic mechanical thrombectomy of cerebral venous thrombosis in a pediatric patient: Case Report.  J Neurosurg: Pediatrics 11:140-143, 2013
Mattei T, Martin M, Nowak K, Smith D, Yee J , Goulart C, Zborowski A , Lin  J:  Addressing the siphoning effect in new shunt designs by decoupling the activation pressure and the pressure gradient across the valve: Technical note.   J Neurosurg: Pediatrics11:181-187, 2013
Neils DM, Wang H, Lin J: Endoscopic third ventriculostomy for shunt malfunction: What to do with the shunt? Surg Neurol Int 4(1):3, 2013
Mattei T, Salma A, Lin J.  Spontaneous bowel perforation from distal catheter leading to meningitis: a rare but frequently overlooked complication of ventriculo-peritoneal shunts.  Pediatr Neurol 48:477-478, 2013
Mattei TA, Frank C, Bailey J, Lesle E, Macuk A, Lesniak M, Patel A, Morris MJ, Nair K, Lin J: Design of a synthetic simulator for pediatric lumbar spine pathologies. J Neurosurg Pediatrics 12:192-201, 2013


Mattei TA: "…mAB": Can we dream with a future monoclonal antibody therapy for lumbar canal stenosis. World Neurosurg 78(3-4): 197, 2012
Mattei TA, Dinh DH: Myelopathy in patients under chronic steroid therapy: remember spinal epidural lipomatosis. Spine J 13:1163-1164, 2013
Mattei TA, Fassett DR: Combined S1-and S2 sacral alar-iliac screws as a salvage technique for pelvic fixation after pseudarthrosis and lumbosacropelvic instability. J Neurosurg Spine 19(3): 321-330, 2013
Mattei TA, Fassett DR: Low-profile pelvic fixation with sacral alar-iliac screws. Acta Neurochir 155(2):293-297, 2013
Mattei TA, Hanovnikian J, Dinh DH: Progressive kyphotic deformity in comminuted burst fractures treated non-operatively: the Achilles tendon of the Thoracolumbar Injury Classification and Severity Score (TLICS). Eur Spine J 23:2255-2262, 2014
Godil SS, McGirt MJ, Glassman SD, Knightly JJ, Mummaneni PV, Oetting G, Theodore N, Gottfried ON, Khairi S, Schmidt MH, Boakye M, Kalkanis SN, Rabin D, Ryken TC, Balturshot GW, Chadduck J, Fassett D, et al: Defining the effectiveness of lumbar spine surgery in a nationwide prospective longitudinal quality of life registry: an analysis of variability in patient-reported outcomes and preliminary predictive models of treatment failure. Neurosurgery 61 Suppl 1: 194-195, 2014

Stroke / Cerebrovascular

Liu LP, Zheng HG Wang DZ, Wang YL, Hussain M, Sun HX, Wang AX, Zhao XQ, Dong KH, Wag CX, He W, Ning B, Wang YJ. Risk assessment of deep-vein thrombosis after acute stroke: a prospective study using clinical factors. CNS Neurosci Ther 20(5): 403-410, 2014
Chelluboina B, Klopfenstein JD, Gujrati M, Rao JS, Veeravalli KK: Temporal regulation of apoptotic and anti-apoptotic molecules after middle cerebral artery occlusion followed by reperfusion. Mol Neurobiol 49(1): 50-65, 2014
Li J, Wang Y, Wang D, Lin J, Wang A, Zhao X, Liu L, Wang C, Wang Y, CHANCE investigators: Glycated albumin predicts the effect of dual and single antiplatelet therapy on recurrent stroke. Neurology, 84:1-6, 2015