At OSF HealthCare Cancer Institute, our commitment to innovation is grounded in a singular purpose: to detect cancer earlier, treat it more effectively and ultimately save more lives. This calling is not theoretical – it is lived out each day through the integration of clinical excellence, advanced technology and a deep commitment to the patients and families we serve. Today, I am proud to share a milestone that reflects the extraordinary work of our teams and the power of our purpose in action.
In May, OSF Cancer Institute will be represented on one of the world’s most prestigious stages, the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. Among more than 8,500 abstracts submitted from across the globe, our research was selected for oral presentation, an honor achieved by less than 1% of submissions.
Our study, “Implementing a centralized navigator-led and AI-assisted platform to improve lung cancer screening rates and early detection: A 6-year health system analysis,” led by Dr. Jun Zhang, vice president of Oncology Research, highlights a six-year transformation in lung cancer screening across our Ministry. Clinically, lung cancer remains the leading cause of cancer-related deaths, largely due to late-stage diagnosis. Increasing screening rates, particularly through low-dose CT (LDCT), is one of the most effective strategies to reduce mortality, yet national uptake has remained persistently low. By implementing a centralized, navigator-led model supported by artificial intelligence, we have more than doubled lung cancer screening rates significantly improving early detection, particularly in rural communities.
This model integrates AI-assisted identification of high-risk patients within the electronic health record with a dedicated navigation infrastructure thereby removing barriers for primary care providers while ensuring timely screening, follow-up and continuity of care. The result is a scalable, data-driven approach that closes critical gaps in access and equity.
This work is more than data, it represents lives changed. Between 2020 and 2025, our screening rates increased from 18.2% to 42.8%, dramatically outpacing the national average. This progression reflects a fundamental shift toward earlier-stage diagnosis where lung cancer is most treatable. and survival outcomes are significantly improved. Notably, our rural facilities experienced some of the greatest gains in Stage 1 detection, reinforcing our commitment to reducing geographic disparities in care.
To be selected for oral presentation at ASCO – attended by more than 40,000 oncology professionals from around the world – is a powerful affirmation that the work happening within OSF HealthCare Cancer Institute is leading the way in shaping the future of cancer care.
This recognition belongs to our physicians, researchers, navigators and care teams who relentlessly pursue better outcomes for our patients. It also belongs to you, our supporters and partners, whose belief in our Mission makes this level of innovation possible.
Together, we are not only advancing care, we are redefining what is possible, bringing hope to patients earlier in their journey, and setting a new standard for cancer care locally, nationally and around the world.
Two Patients. One Purpose. A Future Changed.
At OSF HealthCare Cancer Institute, patients often arrive carrying very different stories, different fears, different diagnoses, different outcomes. Yet sometimes, those paths quietly converge, shaping something far greater than any single journey.
These are two of those stories.
When the first patient came to the gynecologic oncology clinic, she was afraid, but resolute. With a strong family history of ovarian cancer, she trusted her instincts when she felt a pelvic mass. She knew she needed expert care, and she knew where she wanted to receive it. “I wanted to be seen at OSF,” she told her care team. “I trusted the surgical expertise and wanted the best possible outcome.”
When she was invited to participate in the EV Pap research trial, and after discussion with her caregiver, Michelle Rowland, MD, her decision was immediate and deeply personal. Her motivation went beyond her own diagnosis. “I don’t want women to have to wait until there’s a mass to find out something is wrong,” she said. “I wanted to be part of change.”
Her surgery went well. Her pathology came back benign.
At first, she worried that her participation hadn’t mattered; that because she didn’t have cancer, her role in the study had been insignificant. But the opposite was true.
Her noncancerous samples were essential. They helped researchers validate the test’s accuracy and specificity and in answering a critical question: Can this tool reliably distinguish between benign and malignant tissue? Her contribution became part of the scientific foundation that could one day help detect ovarian cancer earlier, when it is most treatable.
Because of the Sister Diane Marie Gynecological Research Fund, the trial existed when she needed it. It wasn’t delayed. It wasn’t theoretical. It was real.
And so was her impact.
The second patient’s journey began differently. An incidental finding led her to the same gynecologic oncology clinic and to surgery she never expected to need. When the research team and Rebecca Byler Dann, MD, approached her about enrolling in the EV Pap trial, she hesitated. She wasn’t sure what to think. She wasn’t sure what to hope for. But she knew she wanted to help.
Her mass did turn out to be cancer.
Even then, especially then, she chose to continue participating in the trial, contributing samples during her standard-of-care oncology visits. She didn’t have to. But she wanted to.
“This is bigger than me,” she shared with her care team. “If my journey can help someone else, then something meaningful can come from this.”
She spoke of her children. And her children’s children. Of a future where families might not have to walk the same difficult road.
Through her participation, she wasn’t just receiving care, she was shaping the future of care.
Two patients. Two outcomes. One shared purpose.
Together, their stories reveal the true power of donor-supported research; patients empowered to transform fear into progress, and uncertainty into hope. Because of generosity, innovation moves forward, and because of courage, the future of cancer care is rewritten every day.
That is the impact of this work.
That is the difference philanthropy makes.
OSF HealthCare Cancer Institute continues to expand its nationally recognized cancer program with the recent recruitment of two highly trained urologic oncologists, Zeynep Gul, MD, and Simon Kim, MD, MPH, both of whom began caring for patients in April.
Urologic oncologists are specialists who diagnose and treat cancers of the genitourinary system, including prostate, bladder, kidney and testicular cancers. Their work often combines complex surgical expertise – ranging from minimally invasive robotic procedures to open surgery – with a deep understanding of cancer biology and multidisciplinary care. As cancer treatments become increasingly personalized, the addition of subspecialists like Drs. Gul and Kim enhances the ability of OSF Cancer Institute to deliver advanced, patient-centered care close to home.
Dr. Gul joins OSF with a strong background in academic medicine and clinical research. Most recently an assistant professor of urology at Washington University School of Medicine, she completed her urology residency at the Icahn School of Medicine at Mount Sinai, where she served as chief resident, followed by a prestigious Society of Urologic Oncology fellowship at the University of Pittsburgh Medical Center. Her academic journey began at Princeton University and continued through Case Western Reserve University School of Medicine. Dr. Gul has received numerous awards for research and clinical excellence and has contributed extensively to peer-reviewed literature in urologic oncology, with a focus on improving outcomes and access to care.
Dr. Kim brings similarly distinguished training and a reputation for surgical excellence. He completed his medical degree at Chicago Medical School, followed by a urology residency at the University of Michigan and a fellowship in urologic oncology at the Mayo Clinic. He also holds a Master of Public Health from the University of Illinois Chicago, reflecting a commitment to both individual patient care and broader population health. Board-certified and nationally recognized, Dr. Kim specializes in treating a wide range of genitourinary cancers using open, laparoscopic and robotic techniques. In addition to his clinical work, he serves as a visiting clinical professor of surgery at University of Illinois College of Medicine Peoria.
Together, Drs. Gul and Kim significantly strengthen the urologic oncology program at OSF HealthCare Cancer Institute – expanding access to leading-edge surgical care, advancing research and innovation, and ensuring patients across the region benefit from the highest level of specialized cancer expertise.
Joshua Parrish is a devoted father of two – his son, Carlin, and daughter, Alijah – and is eagerly anticipating a new role as a grandfather this summer. As he approaches his 50th birthday, Joshua reflects on a journey he never expected to face: a diagnosis of HPV-positive oropharyngeal cancer, a form of squamous cell carcinoma affecting the mouth, throat and palate area. He had developed a large cell tumor in the right side of his mouth and throat area.
“It was a very scary diagnosis that instantly made me feel alone,” Joshua shared. “Very alone.”
But that feeling did not last long.
After nearly a week in the hospital, Joshua was discharged on a Friday with follow-up care scheduled the following Monday at OSF HealthCare Cancer Institute. What awaited him was not just treatment but a team.
“My friends. From the moment I walked in, I realized I wasn’t alone at all,” he said.
Joshua was surrounded by a comprehensive, compassionate care team dedicated to guiding him through every step of his journey. From his nurse navigator and oncology specialists to nutrition, social work, financial counseling and palliative care, each member played a vital role in ensuring he felt informed, supported and confident in his care plan.
“This team was tasked with what felt impossible – helping me feel comfortable with the road ahead – and they did exactly that,” Joshua said.
Beyond clinical care, Joshua found strength in the unwavering support of his loved ones, including his mother, Cathy; his sister, Rachel; and his partner, Kandise. He also credits a friend, Mr. Storm, for encouraging him to seek medical attention – an act Joshua describes as life-saving.
Today, Joshua reflects on his experience with deep gratitude.
“There is nothing I would change about the team that helped me through this journey,” he said. “I truly believe they were placed in my life for a reason.”
Joshua’s story is one of resilience, faith and the power of compassionate care – an inspiring reminder that no one faces cancer alone at OSF HealthCare.
At OSF HealthCare Cancer Institute, philanthropy is doing far more than funding programs and spaces – it is helping create hope, comfort and healing experiences for patients and families facing cancer. Through generous acts of giving, donors are strengthening supportive services and patient care programs that extend beyond medicine alone, ensuring patients receive compassionate, whole-person care throughout their journey.
Recently, two meaningful gift celebrations highlighted the profound impact generosity can have at OSF Cancer Institute and the joy donors themselves experience through giving.
One celebration honored Matt and Lesley Vonachen for their continued commitment and overall support of OSF Cancer Institute. Their generosity has helped advance patient-centered care initiatives and supportive programs designed to meet the emotional, physical and spiritual needs of patients and families navigating cancer treatment.
Another celebration recognized the Parker Family (Drew, Rená, Rob, Kimberly, Penelope and Elle) for their support of The Well, located within the Healing Garden at OSF Cancer Institute. The Healing Garden serves as a place of peace, reflection and renewal for patients, loved ones and team members, while The Well symbolizes restoration, hope and compassion during difficult moments.
While each family’s story and inspiration for giving is unique, both celebrations shared a powerful common theme: the joy of giving during one’s lifetime and the ability to witness the impact generosity can have on others. In addition to the opportunity to leave a legacy in the future, these philanthropists expressed how meaningful it has been to actively see lives touched, programs strengthened and healing environments enhanced through their support today.
Their gifts also reflect an important truth about philanthropy within health care. Charitable support often makes possible the services and programs that surround clinical care: supportive care initiatives, healing spaces, patient navigation, wellness resources and other programs focused on improving quality of life for patients and families.
At OSF Cancer Institute, philanthropy continues to play a vital role in shaping compassionate cancer care. Through the generosity of donors like the Vonachens and the Parker Family, patients are reminded they are surrounded by a community that believes in hope, healing and caring for the whole person.
Third-party fundraising events play a powerful and often underappreciated role in advancing health care and strengthening communities. Organized and led by passionate volunteers, these events extend the reach of Mission-driven organizations like OSF HealthCare Cancer Institute, transforming personal commitment into meaningful impact for patients and families.
At their core, third-party fundraisers are driven by individuals and groups that feel called to make a difference. They bring together neighbors, friends and local businesses around a shared purpose – supporting those facing cancer. In doing so, they not only generate vital financial resources but also foster a sense of unity, hope and compassion that resonates far beyond the day of the event.
Two recent examples illustrate this impact. On Saturday, May 2, more than 700 participants gathered for the 5th Annual Nun Run, a vibrant event that brought the community together in support of cancer care. Whether running, walking, volunteering or cheering from the sidelines, each participant contributed to a collective show of support for patients and families. Events like the Nun Run for Cancer highlight how community engagement can directly support advancements in care, from early detection to survivorship programs, ensuring patients have access to leading-edge treatment close to home.
That same day, approximately 220 participants took part in Shoot for the Cure, a grassroots event founded in 2012 by a group of friends motivated by personal loss. Built on a foundation of community involvement, the event has returned more than $147,000 to local causes. After connecting with OSF HealthCare Cancer Institute in 2024, organizers began directing a portion of proceeds to support its programs, with contributions expected to exceed $30,000 by 2027. Their story underscores how deeply personal experiences can inspire sustained, meaningful philanthropy.
Together, these events demonstrate the unique value of third-party fundraising. They amplify awareness, engage new supporters and provide essential funding that helps expand services and enhance patient care. Most importantly, they remind us that behind every dollar raised is a community standing with those facing cancer proving that when people come together with purpose, the impact is profound.
OSF Breakthrough Treatment Center continues to expand its clinical research portfolio, reflecting impressive progress in building the future of cancer research.
Thanks to our community’s generous support, OSF HealthCare has reached a major milestone: the first patients have now been treated with a promising new therapy in an early-phase clinical trial at OSF HealthCare. These patients, who had exhausted multiple prior treatments, are among only a handful in the United States to receive this innovative approach – offering new hope when options were thought to be exhausted.
OSF HealthCare has recruited an extraordinary foundational research team and is building a growing pipeline of top clinical and research talent eager to join OSF HealthCare and advance its Mission to become a leader in the fight against cancer.
OSF HealthCare has also achieved another groundbreaking milestone: delivering patient-specific clinical decision support to a patient with advanced cancer who already failed prior therapies. This was made possible through a world-leading integration of leading-edge artificial intelligence, computational systems biology, digital twins, in silico trials and other novel approaches. It represents a promising leap forward by combining some of the most sophisticated AI and biological tools with a highly collaborative, multi-disciplinary scientific, clinical and technological teams at multiple research centers.
Recent opened studies include:
Key Research Initiatives: Shaping the Future of Cancer Care
At OSF HealthCare Cancer Institute, innovation meets collaboration to transform cancer care. By leading groundbreaking research, advancing clinical trials and partnering with global academic and industry leaders, our purpose is clear: detect cancer earlier, develop more effective treatments and improve patients' lives.
Early Cancer Detection: Saving Lives Through Innovation
Integrated Early Detection
Pancreatic Cancer Early Detection
Lung Cancer Early Detection
Delivering Personalized and Targeted Treatments
Gynecological Oncology
OSF Breakthrough Treatment Center is at the forefront of clinical trials focused on ovarian, endometrial and cervical cancers. In collaboration with the GOG Foundation and leading industry and academic partners, these trials are pioneering personalized therapies to improve treatment effectiveness and patient care.
Brain Cancer
Key Focus Areas
At OSF HealthCare Cancer Institute, we are committed to supporting our patients and the community with a variety of educational and wellness-focused classes. From cooking and lifestyle tips to informative sessions and supportive group discussions, our classes are designed to empower individuals with the knowledge and tools they need to live well. Whether you're looking to improve your nutrition, learn new coping strategies or connect with others, we offer a range of opportunities to enhance your well-being.
If interested in attending one of our classes, please register through the QR Code or visit osfhealthcare.org/calendar; all dates are subject to change.
| Scan the QR code, scroll to the bottom of the page and search using the class name as Keyword. |
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