The following list contains clinical studies in which the OSF HealthCare Cardiovascular Institute is enrolling patients. For questions or to enroll, please contact our research staff at 309-589-1930 in the Peoria area and 815-395-9181 in Rockford.
Currently Enrolling - Peoria Area
A registry intended to expand the clinical knowledge base on the use of the Aptus™ Heli-FX™ EndoAnchor™ System by including “real world” use over a broad spectrum of geographies, by a wide variety of practicing clinicians, and with a minimal degree of subject selection criteria. For more information, contact Stephanie at (309) 589-1934.
A randomized trial comparing the ELUVIA™ drug-elutIng stent versus Zilver® PTX® stent for treatment of superficial femoral and/or proximal popliteal arteries. For more information, contact Rita at (309) 589-1937.
A randomized clinical study to determine efficacy, safety and tolerability of pulsed, inhaled Nitric Oxide (iNO) versus placebo in symptomatic subjects with pulmonary arterial hypertension. For more information, contact Rita at (309) 589-1937.
STEP Pilot Study
A Supervised TAVR Exercise Program (STEP) for patients prior to undergoing Transcatheter Aortic Valve Replacement. For more information, contact Stephanie at (309) 589-1934.
An ED-Based clinical registry evaluating the utilization of Ticagrelor in the upstream setting for Non-ST-Segment Elevation Acute Coronary Syndrome. For more information, contact Stephanie at (309) 589-1934.
Currently Enrolling - Rockford Area
Peripheral Artery Disease (PAD)
GORE ISR 14-04
A Clinical trial for patients who have already had stents in the legs and are experiencing reoccurring symptoms of PAD. Post-Approval Study of the GORE® VIABAHN® Endoprosthesis for the Treatment of In-Stent Restenosis in the Superficial Femoral Artery. For more information, please contact Joanne at (815) 395-9181.
A Clinical trial for patients with an iliac aneurysm needing treatment. PRESERVE-Zenith® Iliac Branch Clinical Study-Clinical Study to Evaluate the Safety and Effectiveness of the Zenith® Branch Endovascular Graft-Iliac Bifurcation. For more information, please contact Lindsey at (815) 395-9181.
A Clinical trial for patients with long standing Atrial Fibrillation that is now symptomatic. Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach for Treatment of Subjects with Persistent or Long Standing Persistent Atrial Fibrillation with Radio-frequency Ablation. For more information, please contact Melissa at (815) 395-9181.
Follow-Up Only - Peoria Area
A randomized, controlled trial to Evaluate the Absorb™ BVS, the Everolimus Eluting Bioresorbable Vascular Scaffold in the treatment of subjects with de novo native coronary artery lesions. For more information, contact Stephanie at (309) 589-1934.
A prospective cluster-randomized clinical trial that will evaluate whether patient co-payment reduction significantly influences antiplatelet therapy selection and long-term adherence. This study will also examine patient outcomes and the overall cost of care after Acute Myocardial Infarction. For more information, contact Stephanie at (309) 589-1934.
Evaluation of XIENCE versus Coronary Artery Bypass Surgery for effectiveness of left main revascularization. For more information, contact Rita at (309) 589-1937.
A randomized study to evaluate the effect of SAR236553/REGN727 on the occurrence of cardiovascular events in patients who have recently experienced an Acute Coronary Syndrome. . For more information, contact Rita at (309) 589-1937.
A post-PMA approval, prospective, consecutively enrolling, nonrandomized multi-center clinical study to evaluate the safety and effectiveness of the Ovation/Ovation Prime Abdominal Stent Graft System through five years of implantation. For more information, contact Stephanie at (309) 589-1934.
A post approval study evaluating the acute and chronic performance of a Quadripolar CRT-D device system in a patient population indicated for cardiac resynchronization therapy. For more information, contact Stephanie at (309) 589-1934.
A post market study to determine the prevalence and incidence of externalized conductors and other visual lead anomalies (as evidenced by imaging) and the risk of progression to electrical dysfunction in a large series of ICD/ CRT-D/CRT-P devices containing one or more of the following SJM leads: Riata leads, Riata ST silicone leads, Durata leads, QuickSite/QuickFlex CRT leads. For more information, contact Rita at (309) 589-1937.
A Randomized trial to evaluate the effect of Ticagrelor twice daily on the incidence of cardiovascular death, myocardial infarction or stroke in Patients with Type 2 Diabetes Mellitus. For more information, contact Rita at (309) 589-1937.
A post approval study evaluating the long-term safety and performance of the Zenith® TX2 TAA Endovascular Graft in the elective treatment of patients with descending thoracic aortic aneurysms or ulcers. For more information, contact Stephanie at (309) 589-1934.
Follow-Up Only - Rockford Area
Peripheral Artery Disease
A Clinical trial for patients with newly diagnosed PAD. The US StuDy for EvalUation EndovasculaR TreAtments of Lesions in the Superficial Femoral Artery and Proximal Popliteal By usIng the Protégé EverfLex NitInol STent SYstem Post Approval Study.
A clinical trial comparing the safety and efficacy of BIOTRONIK’s Astron and Astron Pulsar stents for the treatment of peripheral artery disease.
A Registry for patients who have/will receive an Optisure defibrillator lead. Optisure Lead Study
A registry evaluating the clinical performance of St. Jude Medical’s Optim™ pacemaker and defibrillator leads.
Coronary Artery Disease
A Clinical trial for patients with coronary artery disease needing stent placement. BioNIR Ridaforolimus Eluting Stent In Coronary Stenosis.
Coronary Artery Disease
A Clinical trial for patients who were in the hospital for a STEMI or NSTEMI and will need anticoagulation for 12 months-enrollment must happen prior to discharge. Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study.
A Clinical trial for patients with heart failure who have been recently hospitalized due to hearth failure. A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Oral Rivaroxaban with Placebo for Reducing the Risk of Death, Myocardial Infarction or Stroke in Subjects with Chronic Heart Failure and Significant Coronary Artery Disease Following a Hospitalization for Exacerbation of Heart Failure.